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针刺联合大秦艽汤口服治疗急性期周围性面瘫的疗效观察
Therapeutic effect of acupuncture combined with Daqinjiao Decoction on acute peripheral facial paralysis
投稿时间:2019-03-13  修订日期:2019-04-09
DOI:
中文关键词:  针刺  大秦艽汤  急性期周围性面瘫  临床疗效
英文关键词:acupuncture  Daqinjiao Decoction  peripheral facial paralysis in acute phase  clinical efficacy
基金项目:广东省中医药局科研项目资助课题(20171090)
作者单位E-mail
黎敏婷△ 广州中医药大学 654546949@qq.com 
张正☒ 广州中医药大学 1704879469@qq.com 
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中文摘要:
      目的:研究针刺联合大秦艽汤口服治疗急性期周围性面瘫的临床疗效。 方法:将72例急性周围性面瘫患者按照随机数字法分为对照组与观察组,每组36例,两组患者均给予泼尼松、阿昔洛韦、维生素B1、甲钴胺等西药常规治疗,对照组予针刺治疗,观察组在对照组基础上加用大秦艽汤口服,连续治疗4周。评价两组治疗的临床疗效,采用House-Brackmann( H-B)面神经功能评价分级,对两组患者治疗前及治疗第7、14、21、28天进行面神经功能评分,并比较两组患者的痊愈时间。 结果:治疗后,观察组总有效率为97.2%,对照组为86.1%(P<0.05);观察组痊愈率为77.8%,对照组58.3%(P<0.05);观察组患者痊愈所需天数与对照组比较,明显缩短,具有显著差异(P<0.01);治疗7天、14天后,观察组H-B评分明显高于对照组,具有显著差异(P<0.01)。治疗组主要不良反应为便秘,发生率约11.1%,经适当调整中药药量后可缓解,对照组不良反应主要表现为胃脘部不适,口干,面部痤疮等,发生率约30.6%。二者发生率具有显著差异(P<0.05)。结论:针刺联合大秦艽汤口服,针药并用,能加速急性期周围性面瘫患者面神经功能恢复,并显著缩短疗程,疗效及安全性较高。
英文摘要:
      Objective: To study the clinical efficacy of acupuncture combined with Daqinjiao Decoction in the treatment of acute peripheral facial paralysis. Methods: 72 patients with acute peripheral facial paralysis were randomly divided into the control group and the observation group. Each group of 36 patients were treated with western medicine such as prednisone, acyclovir, vitamin B1 and mecobalamin. Acupuncture treatment was given on the basis of conventional treatment, and the observation group was given Oral Administration of Daqin Decoction on the basis of the control group for 4 weeks. The clinical efficacy of the two groups of treatments was evaluated. The house-Brackmann (H-B) facial nerve function evaluation was used to evaluate the facial nerve function before treatment and on the 7th, 14th, 21st and 28th day after treatment, and the two groups were cured-time.Results: After treatment, the total effective rate was 97.2% in the observation group and 86.1% in the control group (P<0.05). The cure rate was 77.8% in the observation group and 58.3% in the control group (P<0.05). The number of days required for recovery in the observation group and the control group The group comparison was significantly shortened and had significant difference (P<0.01). After 7 days and 14 days of treatment, the HB score of the observation group was significantly higher than that of the control group, with significant difference (P<0.01). The main adverse reaction in the treatment group was constipation. The incidence rate was about 11.1%. After adjusting the dosage of traditional Chinese medicine, it could be relieved. The adverse reactions in the control group mainly showed stomach discomfort, dry mouth and facial acne, the incidence rate was 30.6%. There was a significant difference in the incidence of both (P<0.05).Conclusion: Acupuncture combined with Daqinjiao Decoction, combined with acupuncture and medicine, can accelerate the recovery of facial nerve function in patients with acute facial paralysis, and significantly shorten the course of treatment, with high efficacy and safety.
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