Abstract：This paper mainly summarizes the acupuncture method of "Tongdu Qishen" from the four aspects of "reasons, methods, prescriptions and skills". The regulation of the function of the five internal organs is the foundation of the filling of the brain, and the Governor vessel plays a key role in the treatment of mental diseases as a bridge between "brain" and "five internal organs". Based on the close relationship among brain-spirit, Governor Meridian and five Zang-organs-spirit, by means of regulating Governor vessels and recuperating the five Zang-organs, and for the purpose of "enlightening spirit ", the concept of "treating spirit" is carried out in the whole process of diagnosis, treatment and recuperation of mental diseases. The meridian of "Governor vessels" is smooth, the functions of "five Zang organs" are in harmony, the sea of marrow is nourished, and the magical machine is opened. Through the re-discussion of Professor Li Zhigang's academic thoughts on the treatment of mental illness, the purpose of this paper is to provide theoretical reference for acupuncture treatment of mental disease.