Objective To observe the clinical effect of Wentong-acupuncture combined with calcium and calcitriol in the treatment of senile primary osteoporosis with intestinal dysfunction. Methods 127 patients with primary OP were randomly divided into two groups: the observation group (63 cases) and the control group (64 cases). The control group was given vitamin D calcium chewing tablets and calcitriol pills. The observation group was given Wentong-acupuncture therapy on the basis of the treatment of the control group. The two groups were treated according to the course of treatment for 6 months. After the treatment, the clinical effect of the two groups was observed. Before and after the treatment, dual energy X-ray bone was used. BMD of lumbar spine, femoral neck and femoral trochanter were measured by densitometer, NBAP, OC, MMP-2, CT, DAO and d-lac were measured by ELISA, and intestinal function was evaluated. Results After treatment, the total effective rate of the observation group was 85.7%, higher than 71.9% of the control group (P<0.05). Compared with before treatment, BMD increased (P<0.05) and serum bone metabolism related indexes improved (P<0.05) in both groups after treatment. Compared with the control group, BMD increased and serum bone metabolism related indexes improved more significantly in the observation group after treatment (P<0.05). The main symptom score, serum Dao and d-lac level of the patients in the observation group decreased after treatment (P<0.05), but there was no statistical significance in the control group (P>0.05); compared with the control group, the main symptom score, Dao and d-lac level of the patients in the observation group decreased after treatment (P<0.05). Conclusion Wentong needle therapy is safe and effective in the treatment of osteoporosis. It can increase bone mineral density, improve bone metabolites and regulate intestinal function. It is a safe, effective and economical treatment method.
目的 观察温通针法联合钙剂及骨化三醇治疗老年原发性骨质疏松伴肠功能障碍的临床疗效。方法 将127例确诊为老年原发性OP的患者，随机分为观察组（63例）和对照组（64例），对照组给予维D钙咀嚼片及骨化三醇胶丸，观察组在对照组治疗基础上，给予温通针法治疗，两组患者均按疗程规范治疗6月，于治疗后观察两组临床疗效，治疗前后采用双能X线骨密度仪检测两组患者腰椎、股骨颈、股骨粗隆BMD，ELISA法检测血清中NBAP、OC、MMP-2、CT及DAO、D-Lac水平，并评价肠道功能。 结果 经治疗后观察组疾病总有效率为85.7%，高于对照组71.9%（P<0.05）；与治疗前比较，两组患者治疗后BMD均增加（P<0.05）、血清骨代谢相关指标均改善（P<0.05）；与对照组比较，观察组治疗后BMD增加及血清骨代谢相关指标改善更明显（P<0.05）；与治疗前比较，观察组患者治疗后肠功能主要症状评分、血清DAO、D-Lac水平下降（P<0.05），对照组虽然上述指标有所下降，但无统计学意义（P＞0.05）；与对照组比较，观察组治疗后肠功能主要症状评分、DAO、D-Lac水平下降（P<0.05）。结论 温通针法治疗骨质疏松症患者安全有效，能够增加骨密度、改善骨代谢产物、调节肠功能，是一种安全、有效、经济的治疗方法。