Gastroesophageal reflux disease (GERD) is one of the common diseases in gastrointestinal tract. Western medicine is mainly used to make acid, but it often occurs repeatedly in clinic, which seriously affects the quality of life of patients. Traditional Chinese medicine treatment is effective in improving the quality of life of patients. Professor Li Jun-xiang integrates “Yi Jing” to learn thinking and put forward the theory of Taiji rise and fall to the left of the liver, spleen and kidney, and the right fall of the heart, stomach and lung, so as to grasp the law of qi movement of the human body as a whole, and to treat gastroesophageal reflux disease (GERD). In clinical practice, we should pay attention to the eight causes of "qi, blood, phlegm, fire, deficiency, blood stasis, dampness and food", and clarify the close relationship between esophageal disease and Zang-fu organs, according to the severity of external acid, reverse and pain to speculate the internal pathogenesis of gastric disharmony and qi deficiency. It is advocated to balance yin and yang Taiji thinking, to "harmony stomach to reduce adverse", combined with the treatment of acid suppressants, and have unique opinions and good curative effect.