Abstract: OBJECTIVE: To summarize the clinical disease spectrum of "dry needle" by searching database, and to compare it with the disease spectrum of acupuncture, so as to clarify the relationship between "dry needle" therapy and acupuncture in traditional Chinese medicine. METHODS: PubMed, EMBASE and Cochrane Library databases were searched by computer for clinical literature related to "dry needle" or “dry needling” from the date of establishment to June 1, 2019. After screening, the disease names of each study were recorded, the number of studies of each disease was counted, and the disease spectrum, theory and operation of acupuncture were compared. RESULTS: A total of 324 clinical studies were included, involving 91 kinds of Western medical diseases. Pain and musculoskeletal symptoms account for more than 90% of the total documents. (2) The dominant diseases of "dry needle" are relatively concentrated, mainly musculoskeletal and myofascial diseases, which belong to pain, arthralgia and meridian diseases of traditional Chinese medicine; (3) the disease spectrum of acupuncture and moxibustion completely covers the content of "dry needle"; the theoretical basis of "dry needle" is correlated to acupuncture; the operation of "dry needle" belongs to the category of acupuncture. Conclusion: "Dry needle" is a modern therapy based on bio-anatomic theory in clinical medicine, with close correlation to acupuncture.