目的：系统评价中药注射剂(CMI)辅助治疗成人支气管哮喘急性发作期的有效性和安全性。方法：计算机检索 PubMed、Cochrane Library、中国知网（CNKI）、中国生物医学文献数据库（CBM）、万方（WanFang）和维普（VIP）数据库（检索时限均从建库至2019年3月），搜集有关临床常用的6种中药注射液（喘可治注射液、痰热清注射液、黄芪注射液、复方丹参注射液、细辛脑注射液、参麦注射液）辅助治疗成人支气管哮喘急性发作期的随机对照试验。对纳入研究进行质量评价和数据提取，用软件gemtc和Stata14做网状Meta分析，用RevMan 5.3作风险偏倚图。结果：纳入18个RCTs、55个半随机对照试验，共计6563例成人支气管哮喘急性发作期患者。网状 Meta 分析显示：①6种CMI与对照组总有效率比较，均优于对照组，具有统计学差异；CMI之间参麦注射液与黄芪注射液间接比较，参麦注射液明显优于黄芪注射液，差异具有统计学意义，其余均无统计学差异。②6种CM辅助治疗成人支气管哮喘急性发作，根据总有效率的概率排序结果，复方参麦注射液最为显著、依次为丹参注射液、喘可治注射液、细辛脑注射液、痰热清注射液、黄芪注射液。结论：基于目前的证据，6种CMI均能在西医常规治疗成人支气管哮喘急性发作期的基础上提高临床有效率，并且以参麦注射液的效果最好。另外本研究结论仍需要大量设计合理、方法得当的 RCTs给予证实。
Objective: To systematically evaluate the efficacy and safety of traditional Chinese medicine injection (CMI) in the treatment of acute bronchial asthma in adults. Methods: The PubMed, Cochrane Library, China Knowledge Network (CNKI), China Biomedical Literature Database (CBM), Wanfang (WanFang) and VIP (VIP) databases were searched by computer (the search time was from the database to March 2019). Collecting 6 kinds of traditional Chinese medicine injections commonly used in clinical practice (Tiaokezhi Injection, Tanreqing Injection, Huangqi Injection, Compound Danshen Injection, Asarum Injection, Shenmai Injection) to treat acute bronchial asthma in adults Randomized controlled trials. Quality evaluation and data extraction were performed on the included studies. Mesh analysis was performed using the software gemtc and Stata14, and RevMan 5.3 was used as the risk bias map. Results: A total of 6563 adult bronchial asthma patients with acute exacerbations were enrolled in 18 RCTs and 55 semi-randomized controlled trials. The reticular meta-analysis showed that the total effective rate of 16 CMIs compared with the control group was better than that of the control group, which was statistically different. The indirect comparison between Shenmai injection and Astragalus injection was better than that of scutellaria injection. The difference in the injection was statistically significant, and the rest were not statistically different. 26 kinds of CM were used to treat the acute exacerbation of bronchial asthma in adults. According to the results of the total effective rate, the compound Shenmai injection was the most significant, followed by Danshen injection, Chuankezhi injection, Asarum injection, and Tanreqing injection. Liquid, astragalus injection. Conclusion: Based on the current evidence, six kinds of CMI can improve the clinical efficiency based on the routine treatment of adult bronchial asthma in western medicine, and the effect of Shenmai injection is the best. In addition, the conclusions of this study still require a large number of well-designed and well-recognized RCTs to confirm.