微小病变肾病( minimal change disease, MCD)又称类脂性肾病,是导致肾病综合征的最常见病理类型之一,对激素敏感但极易复发,反复发作后可能对激素依赖或耐药,从而影响预后。MCD属中医学“水肿”、“尿浊”、“腰痛”、“癃闭”之范畴,其发病与肺、脾、肾三脏功能失调有关。杨霓芝教授在治疗MCD方面有着深厚的造诣,使用中医药改善MCD患者中大量蛋白尿、低蛋白血症、高度水肿的临床症状有一定疗效,配合激素治疗,可减轻药物副作用,提高疗效,降低复发率和不良反应发生率。
Minimal change disease (MCD), also known as lipid-induced nephropathy, is one of the most common pathological types of nephrotic syndrome. It is sensitive to hormones but is highly recurrent. It may be hormone-dependent or resistant after repeated episodes,Influencing prognosis.MCD belongs to the category of &quot;edema&quot;, &quot;urine turbidity&quot;, &quot;low back pain&quot; and &quot;stagnation&quot; in Chinese medicine. Its pathogenesis is related to the dysfunction of lung, spleen and kidney.Professor Yang Nizhi has a profound knowledge in the treatment of MCD. The use of traditional Chinese medicine to improve the clinical symptoms of massive proteinuria, hypoproteinemia and high edema in MCD patients has a certain effect. With hormone therapy, it can reduce the side effects of drugs and improve the curative effect. Reduce the rate of recurrence and the incidence of adverse reactions.