阿尔茨海默病（AD）是最常见的年龄相关的神经系统退行性疾病，年龄是AD最重要的危险因素。神经递质紊乱、氧化应激、Aβ蛋白聚集、tau 蛋白过度磷酸化、线粒体结构和功能异常、慢性炎症等被认为是 AD 的主要发病机制。炎症反应在AD的发生及进程中发挥重要作用。炎症/免疫细胞激活，细胞因子和补体系统调节功能紊乱，外周淋巴细胞的入侵对AD的发生发展产生错综复杂的影响。抗炎治疗，尤其是天然抗炎化合物在防治AD中的作用已经引起了人们的重视。本文对抗炎中药用于预防AD的研究做一小结。
Alzheimer's disease is a degenerative disease of the central nervous system, which has brought heavy economic and spiritual burden to society and patient families. It is urgent to treat it early so as to minimize the harm of this serious disease.The pathological process of Alzheimer's disease is very complex, and the process of disease is often accompanied by neuroinflammation.Neuroinflammation plays a double-edged role in the occurrence and progression of disease. Dysfunction of immune cells, kinin system and complement system , activation of glia and complements, invasion of lymphocyte and infiltration of inflammatory mediators are important components of neuroinflammation. They may promote or endanger the survival of neurons and have a complex impact on the occurrence and development of Alzheimer's disease.In recent years, the use of traditional Chinese medicine in the treatment of neuroinflammatory diseases has gradually become a research hotspot.Many natural compounds have been found to inhibit neuroinflammation, some of which have significant preventive effects on Alzheimer's disease.In this paper, we summarize the natural compounds which have anti-neuroinflammation effect and can be used to prevent Alzheimer's disease in recent years.